Elucidate ai
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Herein, we report a CO2 stimulus for controlled release of p.p.m.-level functional gases from solid materials. Although solid materials that release gas molecules under external stimuli exist, they require an external energy or a device for reliable operation. The concept presented here is generally applicable and offers a solution for several issues that are inherently present in chemiresistive sensing systems.ĭifficulties related to handling gases are a common bottleneck for applications. Moreover, though the sensor monitors the variation of normalized electric resistance (ΔR/R0) in the SWCNT network, temporary deactivation of CR yields a sensor system that does not require analyte-free air for a baseline correction (i.e., estimation of R0) and recovery of response. False responses that occur in the main sensor are easily discriminated by reference sensors that partially employ CR. HCl works as a strong dopant for single-walled carbon nanotubes (SWCNTs), enabling the main sensor to detect ethylene with excellent sensitivity (10.9% ppm-1) and limit of detection (0.2 ppm) in 5 min. Ethylene was converted to acetaldehyde through a Pd-catalyzed heterogeneous Wacker reaction at 40 ☌, followed by condensation with hydroxylamine hydrochloride to emit HCl vapor. Herein, we report a concept of combining a cascade reaction (CR) and a chemiresistive sensor array for sensitive and selective detection of a target analyte (herein, ethylene in air). However, detection of nonpolar chemical substances is often challenging because of the weakness of the doping effect.
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Our results show that BLOX is useful for chemical repurposing, and we expect this search method to have numerous applications in various scientific disciplines.Ĭhemiresistive sensors, which are based on semiconducting materials, offer real-time monitoring of environment. Using absorption spectroscopy, we experimentally verified that eight compounds identified as outstanding exhibit the expected optical properties.
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Our goal is to minimize the number of density functional theory calculations required to discover out-of-trend compounds in the intensity-wavelength property space. We demonstrate the effectiveness of BLOX by finding light-absorbing molecules from a drug database. Unlike other objective-free exploration methods, a boundary for the materials properties is not needed hence, BLOX is suitable for open-ended scientific endeavors. Herein, we propose a new algorithm for automated materials discovery called BoundLess Objective-free eXploration (BLOX) that uses a novel criterion based on kernel-based Stein discrepancy in the property space. This process may not be properly modeled by black-box optimization because the target property is not well defined in some cases. Materials chemists develop chemical compounds to meet often conflicting demands of industrial applications.
ELUCIDATE AI GENERATOR
This inexpensive and disposable NO generator will facilitate NO inhalation therapy in developing countries and nonhospital locations. This work demonstrates that the interlayer nanospace of LDH serves as a reaction mediator for excellent controllability of solid-state reactions.
ELUCIDATE AI PORTABLE
Degradation of the solid mixture is suppressed under dry conditions, so that a portable cartridge column that is readily available as an NO source for emergency situations can be prepared. In contrast to the previously reported NLDH prepared using an anion-exchange method, the reconstructed NLDH exhibits stable and persistent generation of NO because of partial deformation of the layered structures (e.g., particle aggregation, reduced crystallinity, and enhanced basicity). Humid air promotes anion exchange between NO2- and SO42- in the solid mixture, resulting in persistent interactions of NO2- and Fe2+, generating NO.
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This one-pot, organic solvent-free process can be performed at large scales and is suitable for mass production. Mg/Al-type LDH was calcined at 550 ☌ to remove interlayer CO32- and then treated with NaNO2 in water to reconstruct the NLDH. Here we report that a solid mixture of FeIISO4♷H2O and a layered double hydroxide (LDH) containing nitrite (NO2-) in the interlayer spaces (NLDH) stably generates NO at a therapeutic level (â❄0 ppm over 12 h from freshly mixed solids â❈0 ppm for 5-10 h from premixed solids) under air flow (0.25 L min-1) if the NLDH has been prepared by using a reconstruction method. However, its wide adoption has been limited by the lack of a convenient delivery technique of this unstable gas. The inhalation of nitric oxide (NO), which acts as a selective vasodilator of pulmonary blood vessels, is an established medical treatment.